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Upingbio
SKU:YP-Ab-07854-100UL
DLL4 Polyclonal Antibody
DLL4 Polyclonal Antibody
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- Gene Name: DLL4 UNQ1895/PRO4341
- Immunogen: Synthesized peptide derived from part region of human protein
- Specificity: DLL4 Polyclonal Antibody detects endogenous levels of protein.
- Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. [provided by RefSeq, Jul 2008],
- Function: domain:The Delta-Serrate-Lag2 (DSL) domain is required for binding to the Notch receptor.,function:Plays a role in the Notch signaling pathway. Activates Notch-1 and Notch-4.,PTM:Ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation.,similarity:Contains 1 DSL domain.,similarity:Contains 8 EGF-like domains.,subunit:Binds to Notch-1 and Notch-4.,tissue specificity:Expressed in vascular endothelium.,
- Species: Human;Mouse
- Range: WB;ELISA
- Protein: Delta-like protein 4 (Drosophila Delta homolog 4) (Delta4)
- DA: 75kD
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