• ABI3 Polyclonal Antibody
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Upingbio

YP-Ab-07700-100UL

ABI3 Polyclonal Antibody

ABI3 Polyclonal Antibody

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  • Gene Name: ABI3 NESH
  • Immunogen: Synthesized peptide derived from part region of human protein AA range: 286-336
  • Specificity: ABI3 Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],
  • Function: function:May inhibit tumor metastasis (By similarity). In vitro, reduces cell motility.,similarity:Belongs to the ABI family.,similarity:Contains 1 SH3 domain.,subcellular location:Colocalizes with PAK2 at leading edge of cells.,subunit:May interact with PAK1 and PAK2. Probably interacts with TARSH.,tissue specificity:Expressed in heart, lung, liver, pancreas, kidney, placenta and at low levels in brain and skeletal muscle.,
  • Species: Human;Mouse
  • Range: WB;ELISA
  • Protein: ABI gene family member 3 (New molecule including SH3) (Nesh)
  • DA: 40kD
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