• TA2R Polyclonal Antibody
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Upingbio

YP-Ab-07546-100UL

TA2R Polyclonal Antibody

TA2R Polyclonal Antibody

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  • Gene Name: TBXA2R
  • Immunogen: Synthesized peptide derived from human protein . at AA range: 230-310
  • Specificity: TA2R Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: thromboxane A2 receptor(TBXA2R) Homo sapiens This gene encodes a member of the G protein-coupled receptor family. The protein interacts with thromboxane A2 to induce platelet aggregation and regulate hemostasis. A mutation in this gene results in a bleeding disorder. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009],
  • Function: disease:Defects in TBXA2R are the cause of a dominantly inherited bleeding disorder [MIM:188070].,function:Receptor for thromboxane A2 (TXA2), a potent stimulator of platelet aggregation. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. In the kidney, the binding of TXA2 to glomerular TP receptors causes intense vasoconstriction. Activates phospholipase C. Isoform 1 activates adenylyl cyclase, isoform 2 inhibits adenylyl cyclase.,similarity:Belongs to the G-protein coupled receptor 1 family.,
  • Species: Human;Rat;Mouse
  • Range: WB;ELISA
  • Protein: Thromboxane A2 receptor (TXA2-R) (Prostanoid TP receptor)
  • DA: 37kD
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