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Upingbio
SKU:YP-Ab-07539-100UL
PTH2R Polyclonal Antibody
PTH2R Polyclonal Antibody
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- Gene Name: PTH2R PTHR2
- Immunogen: Synthesized peptide derived from human protein . at AA range: 160-240
- Specificity: PTH2R Polyclonal Antibody detects endogenous levels of protein.
- Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: The protein encoded by this gene is a member of the G-protein coupled receptor 2 family. This protein is a receptor for parathyroid hormone (PTH). This receptor is more selective in ligand recognition and has a more specific tissue distribution compared to parathyroid hormone receptor 1 (PTHR1). It is activated only by PTH and not by parathyroid hormone-like hormone (PTHLH) and is particularly abundant in brain and pancreas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013],
- Function: function:This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTH2R may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTH2R presence in neurons indicates that it may function as a neurotransmitter receptor.,similarity:Belongs to the G-protein coupled receptor 2 family.,subunit:Binds to TIPF39/TIP39.,tissue specificity:Expressed abundantly in brain and pancreas. Also expressed in the testis.,
- Species: Human;Rat;Mouse
- Range: WB;ELISA
- Protein: Parathyroid hormone 2 receptor (PTH2 receptor)
- DA: 60kD
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