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SKU:YP-Ab-07306-100UL
ID3 Polyclonal Antibody
ID3 Polyclonal Antibody
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- Gene Name: ID3 1R21 BHLHB25 HEIR1
- Immunogen: Synthesized peptide derived from human protein . at AA range: 68-117
- Specificity: ID3 Polyclonal Antibody detects endogenous levels of protein.
- Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with other HLH proteins. However, the encoded protein lacks a basic DNA-binding domain and therefore inhibits the DNA binding of any HLH protein with which it interacts. [provided by RefSeq, Aug 2011],
- Function: function:ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. ID-3 inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. May inhibit other transcription factors.,induction:By phorbol 12-myristate 13-acetate (PMA).,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Interacts with COPS5 and COPS7A (By similarity). Homodimer, and heterodimer with other HLH proteins.,tissue specificity:Expressed abundantly in lung, kidney and adrenal gland, but not in adult brain.,
- Species: Human;Mouse;Rat
- Range: WB;ELISA
- Protein: DNA-binding protein inhibitor ID-3 (Class B basic helix-loop-helix protein 25) (bHLHb25) (Helix-loop-helix protein HEIR-1) (ID-like protein inhibitor HLH 1R21) (Inhibitor of DNA binding 3)
- DA: 13kD
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