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Upingbio
SKU:YP-Ab-07283-100UL
FXYD5 Polyclonal Antibody
FXYD5 Polyclonal Antibody
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- Gene Name: FXYD5 DYSAD IWU1 HSPC113 UNQ2561/PRO6241
- Immunogen: Synthesized peptide derived from human protein . at AA range: Internal
- Specificity: FXYD5 Polyclonal Antibody detects endogenous levels of protein.
- Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: FXYD domain containing ion transport regulator 5(FXYD5) Homo sapiens This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIC (Related to Ion Channel). FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, is a glycoprotein that functions in the up
- Function: function:Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis.,PTM:Glycosylated.,similarity:Belongs to the FXYD family.,
- Species: Human;Rat;Mouse;
- Range: WB;ELISA
- Protein: FXYD domain-containing ion transport regulator 5 (Dysadherin)
- DA: 19kD
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