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Upingbio
SKU:YP-Ab-07269-100UL
CLC2D Polyclonal Antibody
CLC2D Polyclonal Antibody
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- Gene Name: CLEC2D CLAX LLT1 OCIL
- Immunogen: Synthesized peptide derived from human protein . at AA range: 40-120
- Specificity: CLC2D Polyclonal Antibody detects endogenous levels of protein.
- Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: This gene encodes a member of the natural killer cell receptor C-type lectin family. The encoded protein inhibits osteoclast formation and contains a transmembrane domain near the N-terminus as well as the C-type lectin-like extracellular domain. Several alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Oct 2010],
- Function: function:Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon-gamma. Binds high molecular weight sulfated glycosaminoglycans.,induction:Up-regulated by IL-1alpha and prostaglandin E2 in cultured osteogenic sarcoma cells.,online information:LLT1,similarity:Contains 1 C-type lectin domain.,tissue specificity:Detected in peripheral blood leukocytes, osteoblasts, lymph node, thymus and spleen.,
- Species: Human;Mouse
- Range: WB;ELISA
- Protein: C-type lectin domain family 2 member D (Lectin-like NK cell receptor) (Lectin-like transcript 1) (LLT-1) (Osteoclast inhibitory lectin)
- DA: 21kD
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