• SLAF6 Polyclonal Antibody
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Upingbio

YP-Ab-07249-100UL

SLAF6 Polyclonal Antibody

SLAF6 Polyclonal Antibody

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  • Gene Name: SLAMF6 KALI UNQ6123/PRO20080
  • Immunogen: Synthesized peptide derived from human protein . at AA range: 20-100
  • Specificity: SLAF6 Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, May 2010],
  • Function: function:Triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors.,PTM:Phosphorylated.,similarity:Contains 1 Ig-like (immunoglobulin-like) domain.,subunit:Homodimer. Interacts with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP.,tissue specificity:Expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes.,
  • Species: Human;Mouse
  • Range: WB;ELISA
  • Protein: SLAM family member 6 (Activating NK receptor) (NK-T-B-antigen) (NTB-A) (CD antigen CD352)
  • DA: 36kD
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