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Upingbio

SKU:YP-Ab-07244-100UL

FABP5 Polyclonal Antibody

FABP5 Polyclonal Antibody

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  • Gene Name: FABP5
  • Immunogen: Synthesized peptide derived from human protein . at AA range: 40-120
  • Specificity: FABP5 Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus.[provided by RefSeq, Feb 2011],
  • Function: domain:Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.,function:High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation.,similarity:Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.,tissue specificity:Keratinocytes; highly expressed in psoriatic skin.,
  • Species: Human;Rat;Mouse
  • Range: WB;ELISA
  • Protein: Fatty acid-binding protein, epidermal (Epidermal-type fatty acid-binding protein) (E-FABP) (Fatty acid-binding protein 5) (Psoriasis-associated fatty acid-binding protein homolog) (PA-FABP)
  • DA: 14kD
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