• HECAM Polyclonal Antibody
1 1

Upingbio

YP-Ab-07236-100UL

HECAM Polyclonal Antibody

HECAM Polyclonal Antibody

$0.00 USD
$0.00 USD
Sale Sold out
Shipping calculated at checkout.
Size
  • Gene Name: HEPACAM
  • Immunogen: Synthesized peptide derived from human protein . at AA range: 10-90
  • Specificity: HECAM Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: The protein encoded by this gene is a single-pass type I membrane protein that localizes to the cytoplasmic side of the cell membrane. The encoded protein acts as a homodimer and is involved in cell motility and cell-matrix interactions. The expression of this gene is downregulated or undetectable in many cancer cell lines, so this may be a tumor suppressor gene. [provided by RefSeq, Jul 2011],
  • Function: caution:Product of a dubious CDS prediction. Encoded by the 3'-UTR of HEPACAM.,domain:The cytoplasmic domain plays an important role in regulation of cell-matrix adhesion and cell motility.,function:Involved in regulating cell motility and cell-matrix interactions. May inhibit cell growth through suppression of cell proliferation.,induction:Down-regulated in 20 out of 23 of hepatocellular carcinoma (HCC) samples and is undetectable in 5 HCC cell lines tested.,PTM:N-glycosylated.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subcellular location:In MCF7 breast carcinoma and hepatic Hep3B and HepG2 cell lines, localization of HEPACAM is cell density-dependent. In well spread cells, localized to punctate structures in the perinuclear membrane, cytoplasm, and at cell surface of protusions. In confluent c
  • Species: Human;Mouse
  • Range: WB;ELISA
  • Protein: Hepatocyte cell adhesion molecule (Protein hepaCAM)
  • DA: 45kD
View full details