• LAX1 Polyclonal Antibody
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Upingbio

YP-Ab-07199-100UL

LAX1 Polyclonal Antibody

LAX1 Polyclonal Antibody

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  • Gene Name: LAX1 LAX
  • Immunogen: Synthesized peptide derived from human protein . at AA range: 30-110
  • Specificity: LAX1 Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: function:Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells.,induction:Up-regulated in T-cells following TCR engagement.,PTM:Phosphorylated on tyrosines by Syk, Lck or ZAP70 upon TCR or BCR activation; which leads to the recruitment of GRB2, PIK3R1 and GRAP2.,subunit:When phosphorylated, interacts with GRB2, PIK3R1 and GRAP2.,tissue specificity:Expressed in spleen, thymus, and peripheral blood leukocytes. Expressed in several B-, T-, NK and monocyte cell lines.,
  • Function: function:Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells.,induction:Up-regulated in T-cells following TCR engagement.,PTM:Phosphorylated on tyrosines by Syk, Lck or ZAP70 upon TCR or BCR activation; which leads to the recruitment of GRB2, PIK3R1 and GRAP2.,subunit:When phosphorylated, interacts with GRB2, PIK3R1 and GRAP2.,tissue specificity:Expressed in spleen, thymus, and peripheral blood leukocytes. Expressed in several B-, T-, NK and monocyte cell lines.,
  • Species: Human;Rat;Mouse
  • Range: WB;ELISA
  • Protein: Lymphocyte transmembrane adapter 1 (Linker for activation of X cells) (Membrane-associated adapter protein LAX)
  • DA: 43kD
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