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SKU:YP-Ab-07193-100UL
TRML2 Polyclonal Antibody
TRML2 Polyclonal Antibody
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- Gene Name: TREML2 C6orf76 TLT2 UNQ6268/PRO20473
- Immunogen: Synthesized peptide derived from human protein . at AA range: 30-110
- Specificity: TRML2 Polyclonal Antibody detects endogenous levels of protein.
- Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: TREML2 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 (MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties (Allcock et al., 2003 [PubMed 12645956]).[supplied by OMIM, Mar 2008],
- Function: function:Cell surface receptor that may play a role in the innate and adaptive immune response. Acts as a counterreceptor for CD276 and interaction with CD276 on T-cells enhances T-cell activation.,induction:Induced in CD4 T-cells by concanavalin A.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with CD276 and this interaction enhances T-cell activation.,tissue specificity:Detected in cultured B cells, T cell leukemia and monocyte leukemia. Expressed constitutively on CD8 T-cells and induced on CD4 T-cells after activation.,
- Species: Human;Mouse
- Range: WB;ELISA
- Protein: Trem-like transcript 2 protein (TLT-2) (Triggering receptor expressed on myeloid cells-like protein 2)
- DA: 35kD
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