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Upingbio
SKU:YP-Ab-07183-100UL
CRHBP Polyclonal Antibody
CRHBP Polyclonal Antibody
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- Gene Name: CRHBP CRFBP
- Immunogen: Synthesized peptide derived from human protein . at AA range: 70-150
- Specificity: CRHBP Polyclonal Antibody detects endogenous levels of protein.
- Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy. [provided by RefSeq, Jul 2008],
- Function: function:Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.,
- Species: Human;Rat;Mouse
- Range: WB;ELISA
- Protein: Corticotropin-releasing factor-binding protein (CRF-BP) (CRF-binding protein) (Corticotropin-releasing hormone-binding protein) (CRH-BP)
- DA: 35kD
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