• TNR21 Polyclonal Antibody
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Upingbio

YP-Ab-07154-100UL

TNR21 Polyclonal Antibody

TNR21 Polyclonal Antibody

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  • Gene Name: TNFRSF21 DR6 UNQ437/PRO868
  • Immunogen: Synthesized peptide derived from human protein . at AA range: 430-510
  • Specificity: TNR21 Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its death domain, the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein, which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. [provided by RefSeq, Jul 2013],
  • Function: caution:It is uncertain whether Met-1 or Met-25 is the initiator.,function:May activate NF-kappa-B and JNK and promote apoptosis.,similarity:Contains 1 death domain.,similarity:Contains 4 TNFR-Cys repeats.,subunit:Associates with TRADD.,tissue specificity:Highly expressed in heart, brain, placenta, pancreas, lymph node, thymus and prostate. Detected at lower levels in lung, skeletal muscle, kidney, testis, uterus, small intestine, colon, spleen, bone marrow and fetal liver. Very low levels were found in adult liver and peripheral blood leukocytes.,
  • Species: Human;Mouse
  • Range: WB;ELISA
  • Protein: Tumor necrosis factor receptor superfamily member 21 (Death receptor 6) (CD antigen CD358)
  • DA: 72kD
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