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Upingbio

SKU:YP-Ab-07142-100UL

TNR14 Polyclonal Antibody

TNR14 Polyclonal Antibody

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  • Gene Name: TNFRSF14 HVEA HVEM UNQ329/PRO509
  • Immunogen: Synthesized peptide derived from human protein . at AA range: 190-270
  • Specificity: TNR14 Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: This gene encodes a member of the TNF (tumor necrosis factor) receptor superfamily. The encoded protein functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],
  • Function: function:Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells.,PTM:N-glycosylated.,similarity:Contains 3 TNFR-Cys repeats.,subunit:Interacts with TRAF2, TRAF3 and TRAF5.,tissue specificity:Widely expressed, with the highest expression in lung, spleen and thymus.,
  • Species: Human;Rat;Mouse;
  • Range: WB;ELISA
  • Protein: Tumor necrosis factor receptor superfamily member 14 (Herpes virus entry mediator A) (Herpesvirus entry mediator A) (HveA) (Tumor necrosis factor receptor-like 2) (TR2) (CD antigen CD270)
  • DA: 31kD
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