• C1D Polyclonal Antibody
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Upingbio

YP-Ab-07056-100UL

C1D Polyclonal Antibody

C1D Polyclonal Antibody

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  • Gene Name: C1D
  • Immunogen: Synthesized peptide derived from part region of human protein
  • Specificity: C1D Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: The protein encoded by this gene is a DNA binding and apoptosis-inducing protein and is localized in the nucleus. It is also a Rac3-interacting protein which acts as a corepressor for the thyroid hormone receptor. This protein is thought to regulate TRAX/Translin complex formation. Alternate splicing results in multiple transcript variants that encode the same protein. Multiple pseudogenes of this gene are found on chromosome 10.[provided by RefSeq, Jun 2010],
  • Function: function:Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA. Forms a multi-subunit complex with MPP6 and EXOSC10 and this complex along with MTR4 is required for the 3'-5' end processing of the 5.8S rRNA. Can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. Can induce apoptosis in a TP53/p53 dependent manner. May regulate the TRAX/TSN complex formation. Potentiates transcriptional repression by NR1D1 and THRB.,induction:By gamma-radiation.,PTM:Phosphorylated by PRKDC.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the C1D family.,subcellular location:EXOSC10 is required for nucleolar localization.,subunit:Monomer and homodimer. Interacts with NR1D1, THRA, THRB, NCOR1 and NCOR2 (By similarity). Interacts with EXOSC10. Forms a heterotrime
  • Species: Human;Mouse
  • Range: WB;ELISA
  • Protein: Nuclear nucleic acid-binding protein C1D (hC1D)
  • DA: 15kD
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