• LFTY1 Polyclonal Antibody
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Upingbio

YP-Ab-07038-100UL

LFTY1 Polyclonal Antibody

LFTY1 Polyclonal Antibody

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  • Gene Name: LEFTY1 LEFTB LEFTYB UNQ278/PRO317
  • Immunogen: Synthesized peptide derived from part region of human protein AA range: 121-170
  • Specificity: LFTY1 Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in left-right asymmetry determination of organ systems during development. This gene is closely linked to both a related family member and a related pseudogene. [provided by RefSeq, Aug 2016],
  • Function: function:Required for left-right axis determination as a regulator of LEFTY2 and NODAL.,PTM:The processing of the protein may also occur at the second R-X-X-R site located at AA 132-135. Processing appears to be regulated in a cell-type specific manner.,similarity:Belongs to the TGF-beta family.,
  • Species: Human;Mouse
  • Range: WB;ELISA
  • Protein: Left-right determination factor 1 (Left-right determination factor B) (Protein lefty-1) (Protein lefty-B)
  • DA: 40kD
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