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Upingbio
SKU:YP-Ab-07035-100UL
TNR27 Polyclonal Antibody
TNR27 Polyclonal Antibody
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- Gene Name: EDA2R TNFRSF27 XEDAR UNQ2448/PRO5727/PRO34080
- Immunogen: Synthesized peptide derived from part region of human protein
- Specificity: TNR27 Polyclonal Antibody detects endogenous levels of protein.
- Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: The protein encoded by this gene is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains cysteine-rich repeats and a single transmembrane domain. This protein binds to the EDA-A2 isoform of ectodysplasin, which plays an important role in maintenance of hair and teeth. Alternatively spliced transcript variants encodes distinct protein isoforms. [provided by RefSeq, Apr 2016],
- Function: function:Receptor for EDA isoform A2, but not for EDA isoform A1. Mediates the activation of the NF-kappa-B and JNK pathways. Activation seems to be mediated by binding to TRAF3 and TRAF6.,similarity:Contains 3 TNFR-Cys repeats.,subunit:Associates with TRAF1, TRAF3 and TRAF6.,
- Species: Human;Mouse
- Range: WB;ELISA
- Protein: Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor)
- DA: 32kD
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