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Upingbio
SKU:YP-Ab-06978-100UL
CARF Polyclonal Antibody
CARF Polyclonal Antibody
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- Gene Name: CDKN2AIP CARF
- Immunogen: Synthesized peptide derived from part region of human protein
- Specificity: CARF Polyclonal Antibody detects endogenous levels of protein.
- Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: The protein encoded by this gene regulates the DNA damage response through several different signaling pathways. One such pathway is the p53-HDM2-p21(WAF1) pathway, which is critical to the DNA damage response. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015],
- Function: function:Activates TP53/p53 by CDKN2A-dependent and CDKN2A-independent pathways.,PTM:May be ubiquitinated.,similarity:Belongs to the CARF family.,similarity:Contains 1 DRBM (double-stranded RNA-binding) domain.,subunit:Interacts with CDKN2A/p14ARF, TP53/p53 and MDM2.,tissue specificity:Ubiquitously expressed.,
- Species: Human;Rat;Mouse
- Range: WB;ELISA
- Protein: CDKN2A-interacting protein (Collaborator of ARF)
- DA: 63kD
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