• PTPRM Polyclonal Antibody
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Upingbio

YP-Ab-06974-100UL

PTPRM Polyclonal Antibody

PTPRM Polyclonal Antibody

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  • Gene Name: PTPRM PTPRL1
  • Immunogen: Synthesized peptide derived from part region of human protein. AA range 21-61
  • Specificity: PTPRM Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcrip
  • Function: catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,function:Involved in cell-cell adhesion through homophilic interactions. May play a key role in signal transduction and growth control.,similarity:Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 MAM domain.,similarity:Contains 1 tyrosine-protein phosphatase domain.,similarity:Contains 2 tyrosine-protein phosphatase domains.,similarity:Contains 4 fibronectin type-III domains.,
  • Species: Human;Mouse
  • Range: WB;ELISA
  • Protein: Receptor-type tyrosine-protein phosphatase mu (Protein-tyrosine phosphatase mu) (R-PTP-mu) (EC 3.1.3.48)
  • DA: 159kD
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