• SORC3 Polyclonal Antibody
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Upingbio

YP-Ab-06970-100UL

SORC3 Polyclonal Antibody

SORC3 Polyclonal Antibody

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  • Gene Name: SORCS3 KIAA1059
  • Immunogen: Synthesized peptide derived from part region of human protein
  • Specificity: SORC3 Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: This gene encodes a type-I receptor transmembrane protein that is a member of the vacuolar protein sorting 10 receptor family. Proteins of this family are defined by a vacuolar protein sorting 10 domain at the N-terminus. The N-terminal segment of this domain has a consensus motif for proprotein convertase processing, and the C-terminal segment of this domain is characterized by ten conserved cysteine residues. The vacuolar protein sorting 10 domain is followed by a leucine-rich segment, a transmembrane domain, and a short C-terminal cytoplasmic domain that interacts with adaptor molecules. The transcript is expressed at high levels in the brain, and candidate gene studies suggest that genetic variation in this gene is associated with Alzheimer's disease. Consistent with this observation, knockdown of the gene in cell culture results in an increase in amyloid pre
  • Function: similarity:Contains 1 PKD domain.,similarity:Contains 6 BNR repeats.,tissue specificity:Highly expressed in brain.,
  • Species: Human;Mouse
  • Range: WB;ELISA
  • Protein: VPS10 domain-containing receptor SorCS3
  • DA: 134kD
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