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Upingbio

SKU:YP-Ab-06936-100UL

FHL2 Polyclonal Antibody

FHL2 Polyclonal Antibody

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  • Gene Name: FHL2 DRAL SLIM3
  • Immunogen: Synthesized peptide derived from part region of human protein
  • Specificity: FHL2 Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. This protein is thought to have a role in the assembly of extracellular membranes. Also, this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway. Multiple alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq, Jan 2016],
  • Function: domain:The third LIM zinc-binding mediates interaction with E4F1.,function:May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth.,similarity:Contains 1 LIM zinc-binding domain.,similarity:Contains 3 LIM zinc-binding domains.,similarity:Contains 4 LIM zinc-binding domains.,subunit:Interacts with ZNF638 and TTN/titin. Interacts with E4F1.,tissue specificity:Expressed in skeletal muscle and heart.,
  • Species: Human;Rat;Mouse
  • Range: WB;ELISA
  • Protein: Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3)
  • DA: 30kD
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