• TNR8 Polyclonal Antibody
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Upingbio

YP-Ab-06776-100UL

TNR8 Polyclonal Antibody

TNR8 Polyclonal Antibody

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  • Gene Name: TNFRSF8 CD30 D1S166E
  • Immunogen: Synthesized peptide derived from part region of human protein
  • Specificity: TNR8 Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 IHC-p: 50-200 ELISA 1:5000-20000. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],
  • Function: disease:Most specific Hodgkin disease associated antigen.,function:Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B.,PTM:Phosphorylated on serine and tyrosine residues.,similarity:Contains 6 TNFR-Cys repeats.,subunit:Interacts with TRAF1, TRAF2, TRAF3 and TRAF5.,
  • Species: Human;Rat;Mouse
  • Range: WB;IHC;IF;ELISA
  • Protein: Tumor necrosis factor receptor superfamily member 8 (CD30L receptor) (Ki-1 antigen) (Lymphocyte activation antigen CD30) (CD antigen CD30)
  • DA: 65kD
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