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Upingbio

SKU:YP-Ab-06766-100UL

APOH Polyclonal Antibody

APOH Polyclonal Antibody

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  • Gene Name: APOH B2G1
  • Immunogen: Synthesized peptide derived from part region of human protein
  • Specificity: APOH Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections. [provided by RefSeq, Jul 2008],
  • Function: function:Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.,miscellaneous:In addition to the conflicts shown in the feature table, PubMed:6587378 reports an N-glycosylation site at Asn-188.,online information:The Singapore human mutation and polymorphism database,similarity:Contains 4 Sushi (CCP/SCR) domains.,tissue specificity:Expressed by the liver and secreted in plasma.,
  • Species: Human;Rat;Mouse
  • Range: WB;ELISA
  • Protein: Beta-2-glycoprotein 1 (APC inhibitor) (Activated protein C-binding protein) (Anticardiolipin cofactor) (Apolipoprotein H) (Apo-H) (Beta-2-glycoprotein I) (B2GPI) (Beta(2)GPI)
  • DA: 37kD
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