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Upingbio

SKU:YP-Ab-06746-100UL

PKN3 Polyclonal Antibody

PKN3 Polyclonal Antibody

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  • Gene Name: PKN3 PKNBETA
  • Immunogen: Synthesized peptide derived from part region of human protein
  • Specificity: PKN3 Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,domain:The C1 domain does not bind the diacylglycerol (DAG).,enzyme regulation:Two specific sites, Thr-718 (activation loop of the kinase domain) and Thr-860 (turn motif), need to be phosphorylated for its full activation.,function:Contributes to invasiveness in malignant prostate cancer.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 3 REM (Hr1) repeats.,subcellular location:Nuclear and perinuclear Golgi region.,tissue specificity:Expressed in prostate tumors and various cancer cell lines. Not expressed in adult tissues.,
  • Function: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,domain:The C1 domain does not bind the diacylglycerol (DAG).,enzyme regulation:Two specific sites, Thr-718 (activation loop of the kinase domain) and Thr-860 (turn motif), need to be phosphorylated for its full activation.,function:Contributes to invasiveness in malignant prostate cancer.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 3 REM (Hr1) repeats.,subcellular location:Nuclear and perinuclear Golgi region.,tissue specificity:Expressed in prostate tumors and various cancer cell lines. Not expressed in adult tissues.,
  • Species: Human;Mouse
  • Range: WB;ELISA
  • Protein: Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN-beta) (Protein-kinase C-related kinase 3)
  • DA: 97kD
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