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Upingbio
SKU:YP-Ab-06721-100UL
RASA2 Polyclonal Antibody
RASA2 Polyclonal Antibody
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- Gene Name: RASA2 GAP1M RASGAP
- Immunogen: Synthesized peptide derived from part region of human protein
- Specificity: RASA2 Polyclonal Antibody detects endogenous levels of protein.
- Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014],
- Function: function:Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4).,similarity:Contains 1 Btk-type zinc finger.,similarity:Contains 1 PH domain.,similarity:Contains 1 Ras-GAP domain.,similarity:Contains 2 C2 domains.,
- Species: Human;Mouse;Rat
- Range: WB;ELISA
- Protein: Ras GTPase-activating protein 2 (GAP1m)
- DA: 93kD
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