• ESRP2 Polyclonal Antibody
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Upingbio

YP-Ab-06574-100UL

ESRP2 Polyclonal Antibody

ESRP2 Polyclonal Antibody

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  • Gene Name: ESRP2 RBM35B PP7059
  • Immunogen: Synthesized peptide derived from part region of human protein
  • Specificity: ESRP2 Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: epithelial splicing regulatory protein 2(ESRP2) Homo sapiens ESPR2 is an epithelial cell-type-specific splicing regulator (Warzecha et al., 2009 [PubMed 19285943]).[supplied by OMIM, Aug 2009],
  • Function: function:mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.,induction:Down-regulated during the epithelial-to-mesenchymal transition (EMT).,similarity:Belongs to the ESRP family.,similarity:Contains 3 RRM (RNA recognition motif) domains.,tissue specificity:Epithelial cell-specific.,
  • Species: Human;Mouse
  • Range: WB;ELISA
  • Protein: Epithelial splicing regulatory protein 2 (RNA-binding motif protein 35B) (RNA-binding protein 35B)
  • DA: 79kD
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