• CD27 Polyclonal Antibody
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Upingbio

YP-Ab-06437-100UL

CD27 Polyclonal Antibody

CD27 Polyclonal Antibody

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  • Gene Name: CD27 TNFRSF7
  • Immunogen: Synthesized peptide derived from human protein . at AA range: 1-80
  • Specificity: CD27 Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008],
  • Function: function:Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.,PTM:Phosphorylated and O-glycosylated.,similarity:Contains 3 TNFR-Cys repeats.,subunit:Homodimer. Interacts with SIVA1 and TRAF2.,tissue specificity:Found in most T-lymphocytes.,
  • Species: Human;Rat;Mouse;
  • Range: WB;ELISA
  • Protein: CD27 antigen (CD27L receptor) (T-cell activation antigen CD27) (T14) (Tumor necrosis factor receptor superfamily member 7) (CD antigen CD27)
  • DA: 28kD
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