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Upingbio
SKU:YP-Ab-06430-100UL
CCNG2 Polyclonal Antibody
CCNG2 Polyclonal Antibody
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- Gene Name: CCNG2
- Immunogen: Synthesized peptide derived from human protein . at AA range: 20-100
- Specificity: CCNG2 Polyclonal Antibody detects endogenous levels of protein.
- Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The 8 species of cyclins reported in mammals, cyclins A through H, share a conserved amino acid sequence of about 90 residues called the cyclin box. The amino acid sequence of cyclin G is well conserved among mammals. The nucleotide sequence of cyclin G1 and cyclin G2 are 53% identical. Unlike cyclin G1, cyclin G2 contains a C-terminal PEST protein destabilization motif, suggesting that cyclin G2 expression is tightly regulated through the cell cycle. [provided by RefSeq, Jul 2008],
- Function: developmental stage:Expression levels increase through the cell cycle to peak in the mid/late-S phase and decrease during G2/M phase.,function:May play a role in growth regulation and in negative regulation of cell cycle progesssion.,induction:Activated by actinomycin-D induced DNA damage.,similarity:Belongs to the cyclin family.,similarity:Belongs to the cyclin family. Cyclin G subfamily.,tissue specificity:High levels in cerebellum, thymus, spleen and prostate. Low levels in skeletal muscle.,
- Species: Human;Mouse
- Range: WB;ELISA
- Protein: Cyclin-G2
- DA: 37kD
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