• UBP14 Polyclonal Antibody
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Upingbio

YP-Ab-06336-100UL

UBP14 Polyclonal Antibody

UBP14 Polyclonal Antibody

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  • Gene Name: USP14 TGT
  • Immunogen: Synthesized peptide derived from part region of human protein
  • Specificity: UBP14 Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],
  • Function: catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,caution:Was originally (Ref.1) thought to be a queuine tRNA-ribosyltransferase.,similarity:Belongs to the peptidase C19 family.,similarity:Contains 1 ubiquitin-like domain.,subunit:Homodimer .,
  • Species: Human;Mouse
  • Range: WB;ELISA
  • Protein: Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.4.19.12) (Deubiquitinating enzyme 14) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14)
  • DA: 54kD
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