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Upingbio
SKU:YP-Ab-06193-100UL
DGLA Polyclonal Antibody
DGLA Polyclonal Antibody
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- Gene Name: DAGLA C11orf11 KIAA0659 NSDDR
- Immunogen: Synthesized peptide derived from human protein . at AA range: 900-980
- Specificity: DGLA Polyclonal Antibody detects endogenous levels of protein.
- Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: This gene encodes a diacylglycerol lipase. The encoded enzyme is involved in the biosynthesis of the endocannabinoid 2-arachidonoyl-glycerol.[provided by RefSeq, Nov 2010],
- Function: cofactor:Calcium.,enzyme regulation:Inhibited by p-hydroxy-mercuri-benzoate and HgCl(2), but not to PMSF. Also inhibited by RHC80267, a drug that blocks 2-AG formation.,function:Catalyzes the hydrolysis of diacylglycerol (DAG) to 2-arachidonoyl-glycerol (2-AG), the most abundant endocannabinoid in tissues. Required for axonal growth during development and for retrograde synaptic signaling at mature synapses.,similarity:Belongs to the AB hydrolase superfamily. Lipase family.,tissue specificity:Highly expressed in brain and pancreas.,
- Species: Human;Rat;Mouse
- Range: WB;ELISA
- Protein: Sn1-specific diacylglycerol lipase alpha (DGL-alpha) (EC 3.1.1.-) (Neural stem cell-derived dendrite regulator)
- DA: 114kD
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