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Upingbio

SKU:YP-Ab-06159-100UL

SPB6 Polyclonal Antibody

SPB6 Polyclonal Antibody

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  • Gene Name: SERPINB6 PI6 PTI
  • Immunogen: Synthesized peptide derived from part region of human protein
  • Specificity: SPB6 Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: The protein encoded by this gene is a member of the serpin (serine proteinase inhibitor) superfamily, and ovalbumin(ov)-serpin subfamily. It was originally discovered as a placental thrombin inhibitor. The mouse homolog was found to be expressed in the hair cells of the inner ear. Mutations in this gene are associated with nonsyndromic progressive hearing loss, suggesting that this serpin plays an important role in the inner ear in the protection against leakage of lysosomal content during stress, and that loss of this protection results in cell death and sensorineural hearing loss. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2010],
  • Function: function:Inhibits thrombin.,similarity:Belongs to the serpin family.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,tissue specificity:Highest levels in skeletal muscle. Also found in placenta, cardiac muscle, lung, liver, kidney and pancreas.,
  • Species: Human;Mouse
  • Range: WB;ELISA
  • Protein: Serpin B6 (Cytoplasmic antiproteinase) (CAP) (Peptidase inhibitor 6) (PI-6) (Placental thrombin inhibitor)
  • DA: 41kD
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