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Upingbio
SKU:YP-Ab-06145-100UL
PP1RA Polyclonal Antibody
PP1RA Polyclonal Antibody
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- Gene Name: PPP1R10 CAT53 FB19 PNUTS
- Immunogen: Synthesized peptide derived from part region of human protein
- Specificity: PP1RA Polyclonal Antibody detects endogenous levels of protein.
- Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: This gene encodes a protein phosphatase 1 binding protein. The encoded protein plays a role in many cellular processes including cell cycle progression, DNA repair and apoptosis by regulating the activity of protein phosphatase 1. This gene lies within the major histocompatibility complex class I region on chromosome 6, and alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012],
- Function: function:Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) homopolymers.,PTM:Phosphorylated on Ser-398 and Thr-400 by PKA within the region necessary for interaction with PPP1CA.,similarity:Contains 1 C3H1-type zinc finger.,similarity:Contains 1 TFIIS N-terminal domain.,subcellular location:Found in discrete nucleoplasmic bodies and within nucleoli.,subunit:Interacts with PPP1CA and PPP1CC.,tissue specificity:Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.,
- Species: Human;Mouse;Rat
- Range: WB;ELISA
- Protein: Serine/threonine-protein phosphatase 1 regulatory subunit 10 (MHC class I region proline-rich protein CAT53) (PP1-binding protein of 114 kDa) (Phosphatase 1 nuclear targeting subunit) (Protein FB19) (
- DA: 103kD
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