• RHG20 Polyclonal Antibody
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Upingbio

YP-Ab-06084-100UL

RHG20 Polyclonal Antibody

RHG20 Polyclonal Antibody

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  • Gene Name: ARHGAP20 KIAA1391
  • Immunogen: Synthesized peptide derived from human protein . at AA range: 800-880
  • Specificity: RHG20 Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: The protein encoded by this gene is an activator of RHO-type GTPases, transducing a signal from RAP1 to RHO and impacting neurite outgrowth. [provided by RefSeq, Sep 2016],
  • Function: caution:The translocation involving this gene was originally published as t(X;11)(q13;23) (PubMed:15543602), but BRWD3 is localized to Xq21 and not to Xq13.,developmental stage:Low expression is found in fetal liver.,disease:A chromosomal aberration involving ARHGAP20 may be a cause of B-cell chronic lymphocytic leukemia (B-CLL). Translocation t(X;11)(q21;q23) with BRWD3 does not result in fusion transcripts but disrupts both genes.,function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.,similarity:Contains 1 PH domain.,similarity:Contains 1 Ras-associating domain.,similarity:Contains 1 Rho-GAP domain.,tissue specificity:Expressed predominantly in the brain. Lower expression is found in lymph nodes.,
  • Species: Human;Rat;Mouse;
  • Range: WB;ELISA
  • Protein: Rho GTPase-activating protein 20 (Rho-type GTPase-activating protein 20)
  • DA: 131kD
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