• RBBP6 Polyclonal Antibody
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Upingbio

YP-Ab-06081-100UL

RBBP6 Polyclonal Antibody

RBBP6 Polyclonal Antibody

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  • Gene Name: RBBP6 P2PR PACT RBQ1 My038
  • Immunogen: Synthesized peptide derived from human protein . at AA range: 270-350
  • Specificity: RBBP6 Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. This gene encodes a protein which binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
  • Function: PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,sequence caution:Intron retention.,similarity:Contains 1 CCHC-type zinc finger.,similarity:Contains 1 DWNN domain.,similarity:Contains 1 RING-type zinc finger.,subcellular location:Colocalizes with mitotic chromosomes.,subunit:Interacts with p53/TP53 and RB1.,tissue specificity:Highly expressed in the placenta and testis. Expressed at lower levels in the brain, heart, kidney, liver and lung. Overexpressed in esophageal cancer.,
  • Species: Human;Mouse
  • Range: WB;ELISA
  • Protein: E3 ubiquitin-protein ligase RBBP6 (EC 6.3.2.-) (Proliferation potential-related protein) (Protein P2P-R) (Retinoblastoma-binding Q protein 1) (RBQ-1) (Retinoblastoma-binding protein 6) (p53-associated
  • DA: 197kD
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