• S10A2 Polyclonal Antibody
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Upingbio

YP-Ab-05990-100UL

S10A2 Polyclonal Antibody

S10A2 Polyclonal Antibody

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  • Gene Name: S100A2 S100L
  • Immunogen: Synthesized peptide derived from human protein . at AA range: 40-120
  • Specificity: S10A2 Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: S100 calcium binding protein A2(S100A2) Homo sapiens The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer. [provided by RefSeq, Jul 2008],
  • Function: developmental stage:Preferentially expressed in normal human mammary epithelial cells as opposed to tumor-derived ones. The level of S100L was shown to correlate inversely with tumor progression.,function:May act as a modulator against excess calcium accumulation in normal human mammary epithelial cells. May also play a role in suppressing tumor cell growth.,induction:By growth factors in early G1 phase and probably by cell-cycle regulation in S phase. DNA methylation probably plays a direct negative role in suppressing S100L gene expression in tumor cells.,miscellaneous:This protein binds two calcium ions.,similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,tissue specificity:A subset of epithelial cells including normal human mammary epithelial cells and keratinocytes.,
  • Species: Human;Rat;Mouse;
  • Range: WB;ELISA
  • Protein: Protein S100-A2 (CAN19) (Protein S-100L) (S100 calcium-binding protein A2)
  • DA: 10kD
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