• DCOR Polyclonal Antibody
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Upingbio

YP-Ab-05889-100UL

DCOR Polyclonal Antibody

DCOR Polyclonal Antibody

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  • Gene Name: ODC1
  • Immunogen: Synthesized peptide derived from human protein . at AA range: 250-330
  • Specificity: DCOR Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: ornithine decarboxylase 1(ODC1) Homo sapiens This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2013],
  • Function: catalytic activity:L-ornithine = putrescine + CO(2).,cofactor:Pyridoxal phosphate.,enzyme regulation:Inhibited by S-nitrosylation.,online information:Ornithine decarboxylase entry,pathway:Amine and polyamine biosynthesis; putrescine biosynthesis via L-ornithine pathway; putrescine from L-ornithine: step 1/1.,PTM:S-Nitrosylation inhibits the enzyme. S-Nitrosylated in vitro on 4 cysteine residues.,similarity:Belongs to the Orn/Lys/Arg decarboxylase class-II family.,subunit:Homodimer.,
  • Species: Human;Rat;Mouse
  • Range: WB;ELISA
  • Protein: Ornithine decarboxylase (ODC) (EC 4.1.1.17)
  • DA: 50kD
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