• S22A4 Polyclonal Antibody
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Upingbio

YP-Ab-05888-100UL

S22A4 Polyclonal Antibody

S22A4 Polyclonal Antibody

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  • Gene Name: SLC22A4 ETT OCTN1 UT2H
  • Immunogen: Synthesized peptide derived from human protein . at AA range: 240-320
  • Specificity: S22A4 Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is an organic cation transporter and plasma integral membrane protein containing eleven putative transmembrane domains as well as a nucleotide-binding site motif. Transport by this protein is at least partially ATP-dependent. [provided by RefSeq, Jul 2008],
  • Function: caution:PubMed:9426230 reported that this protein does not transport carnitine, however, experiments were done with the Phe-503 variant, which affects the ability to transport carnitine. PubMed:15459889 showed that, although weakly, it can also transport carnitine at some level. Its function in carnitine transport is therefore unclear.,disease:Defects in SLC22A4 may be a cause of rheumatoid arthritis (RA).,disease:Defects in SLC22A4 may be a cause of susceptibility to Crohn disease (CD) [MIM:266600]. CD is a form of remitting inflammatory bowel disease (IBD). CD may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous. CD is commonly classified as an autoimmune disease.,function:Sodium-ion dependent, low affinity carnitine transporter. Probably transports one sodium ion with one molecule of ca
  • Species: Human;Rat;Mouse;
  • Range: WB;ELISA
  • Protein: Solute carrier family 22 member 4 (Ergothioneine transporter) (ET transporter) (Organic cation/carnitine transporter 1)
  • DA: 60kD
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