• NB5R2 Polyclonal Antibody
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Upingbio

YP-Ab-05808-100UL

NB5R2 Polyclonal Antibody

NB5R2 Polyclonal Antibody

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  • Gene Name: CYB5R2
  • Immunogen: Synthesized peptide derived from human protein . at AA range: 120-200
  • Specificity: NB5R2 Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: The protein encoded by this gene belongs to the flavoprotein pyridine nucleotide cytochrome reductase family of proteins. Cytochrome b-type NAD(P)H oxidoreductases are implicated in many processes including cholesterol biosynthesis, fatty acid desaturation and elongation, and respiratory burst in neutrophils and macrophages. Cytochrome b5 reductases have soluble and membrane-bound forms that are the product of alternative splicing. In animal cells, the membrane-bound form binds to the endoplasmic reticulum, where it is a member of a fatty acid desaturation complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014],
  • Function: catalytic activity:NADH + 2 ferricytochrome b5 = NAD(+) + H(+) + 2 ferrocytochrome b5.,cofactor:FAD.,function:NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction (By similarity). Responsible for NADH-dependent lucigenin chemiluminescence in spermatozoa by reducing both lucigenin and 2-[4-iodophenyl]-3-[4-nitrophenyl]-5-[2,4-disulfophenyl]-2H tetrazolium monosodium salt (WST-1).,similarity:Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.,similarity:Contains 1 FAD-binding FR-type domain.,tissue specificity:Restricted expression.,
  • Species: Human;Rat;Mouse
  • Range: WB;ELISA
  • Protein: NADH-cytochrome b5 reductase 2 (b5R.2) (EC 1.6.2.2)
  • DA: 30kD
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