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Upingbio

SKU:YP-Ab-05762-100UL

MAL Polyclonal Antibody

MAL Polyclonal Antibody

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  • Gene Name: MAL
  • Immunogen: Synthesized peptide derived from human protein . at AA range: 70-150
  • Specificity: MAL Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3. [provided by RefSeq, May 2012],
  • Function: developmental stage:Expressed in the intermediate and late stages of T-cell differentiation.,function:Could be an important component in vesicular trafficking cycling between the Golgi complex and the apical plasma membrane. Could be involved in myelin biogenesis and/or myelin function.,PTM:Lipoprotein.,similarity:Belongs to the MAL family.,similarity:Contains 1 MARVEL domain.,
  • Species: Human;Mouse;Rat
  • Range: WB;ELISA
  • Protein: Myelin and lymphocyte protein (T-lymphocyte maturation-associated protein)
  • DA: 16kD
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