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Upingbio

SKU:YP-Ab-05748-100UL

MNX1 Polyclonal Antibody

MNX1 Polyclonal Antibody

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  • Gene Name: MNX1 HLXB9
  • Immunogen: Synthesized peptide derived from human protein . at AA range: 260-340
  • Specificity: MNX1 Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: This gene encodes a nuclear protein, which contains a homeobox domain and is a transcription factor. Mutations in this gene result in Currarino syndrome, an autosomic dominant congenital malformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009],
  • Function: disease:Defects in MNX1 are a cause of Currarino syndrome [MIM:176450]. The triad of a presacral tumor, sacral agenesis and anorectal malformation constitutes the Currarino syndrome which is caused by dorsal-ventral patterning defects during embryonic development. The syndrome occurs in the majority of patients as an autosomal dominant trait.,function:Putative transcription factor involved in pancreas development and function.,similarity:Contains 1 homeobox DNA-binding domain.,tissue specificity:Expressed in lymphoid and pancreatic tissues.,
  • Species: Human;Mouse
  • Range: WB;ELISA
  • Protein: Motor neuron and pancreas homeobox protein 1 (Homeobox protein HB9)
  • DA: 44kD
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