• LRP1B Polyclonal Antibody
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Upingbio

YP-Ab-05704-100UL

LRP1B Polyclonal Antibody

LRP1B Polyclonal Antibody

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  • Gene Name: LRP1B LRPDIT
  • Immunogen: Synthesized peptide derived from human protein . at AA range: 200-280
  • Specificity: LRP1B Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: IHC-p 1:50-300. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: This gene encodes a member of the low density lipoprotein (LDL) receptor family. These receptors play a wide variety of roles in normal cell function and development due to their interactions with multiple ligands. Disruption of this gene has been reported in several types of cancer. [provided by RefSeq, Jun 2016],
  • Function: function:Potential cell surface proteins that bind and internalize ligands in the process of receptor-mediated endocytosis.,miscellaneous:The gene is preferentially inactivated in one histological type of lung cancer (non-small cell lung cancer (NSCLC)). May thus play an important role in tumorigenesis of NSCLCs.,similarity:Belongs to the LDLR family.,similarity:Contains 14 EGF-like domains.,similarity:Contains 32 LDL-receptor class A domains.,similarity:Contains 36 LDL-receptor class B repeats.,subunit:Binds LRPAP1, PLAU, PLAT and SERPINE1; binding is followed by internalization and degradation of the ligands.,tissue specificity:Expressed in thyroid gland and in salivary gland, as well as in adult and fetal brain.,
  • Species: Human;Mouse
  • Range: IHC;IF
  • Protein: Low-density lipoprotein receptor-related protein 1B (LRP-1B) (Low-density lipoprotein receptor-related protein-deleted in tumor) (LRP-DIT)
  • DA: 505kD
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