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Upingbio

SKU:YP-Ab-05703-100UL

LRP12 Polyclonal Antibody

LRP12 Polyclonal Antibody

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  • Gene Name: LRP12 ST7
  • Immunogen: Synthesized peptide derived from human protein . at AA range: 90-170
  • Specificity: LRP12 Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: This gene encodes a member of the low-density lipoprotein receptor related protein family. The product of this gene is a transmembrane protein that is differentially expressed in many cancer cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010],
  • Function: function:Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor.,similarity:Belongs to the LDLR family.,similarity:Contains 2 CUB domains.,similarity:Contains 5 LDL-receptor class A domains.,subunit:May interact with GNB2L1, MADHIP and ITGB1BP3.,tissue specificity:Widely expressed in heart, skeletal muscle, brain, lung, placenta and pancreas, but not in tissues consisting of a large number of epithelial cells, such as liver and kidney. Expressed at very low levels in a number of tumor-derived cell lines.,
  • Species: Human;Rat;Mouse;
  • Range: WB;ELISA
  • Protein: Low-density lipoprotein receptor-related protein 12 (LRP-12) (Suppressor of tumorigenicity 7 protein)
  • DA: 94kD
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