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Upingbio
SKU:YP-Ab-05592-100UL
FYCO1 Polyclonal Antibody
FYCO1 Polyclonal Antibody
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- Gene Name: FYCO1 ZFYVE7
- Immunogen: Synthesized peptide derived from part region of human protein
- Specificity: FYCO1 Polyclonal Antibody detects endogenous levels of protein.
- Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: FYVE and coiled-coil domain containing 1(FYCO1) Homo sapiens This gene encodes a protein that contains a RUN domain, FYVE-type zinc finger domain and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P) and the autophagosome marker LC3. Mutations in this gene are a cause of autosomal recessive congenital cataract-2 (CATC2). [provided by RefSeq, Dec 2011],
- Function: PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 FYVE-type zinc finger.,similarity:Contains 1 GOLD domain.,similarity:Contains 1 RUN domain.,tissue specificity:Expressed in heart and skeletal muscle.,
- Species: Human;Rat;Mouse;
- Range: WB;ELISA
- Protein: FYVE and coiled-coil domain-containing protein 1 (Zinc finger FYVE domain-containing protein 7)
- DA: 162kD
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