• ELP3 Polyclonal Antibody
1 1

Upingbio

YP-Ab-05570-100UL

ELP3 Polyclonal Antibody

ELP3 Polyclonal Antibody

$0.00 USD
$0.00 USD
Sale Sold out
Shipping calculated at checkout.
Size
  • Gene Name: ELP3
  • Immunogen: Synthesized peptide derived from part region of human protein
  • Specificity: ELP3 Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: ELP3 is the catalytic subunit of the histone acetyltransferase elongator complex, which contributes to transcript elongation and also regulates the maturation of projection neurons (Creppe et al., 2009 [PubMed 19185337]).[supplied by OMIM, Apr 2009],
  • Function: catalytic activity:Acetyl-CoA + histone = CoA + acetylhistone.,cofactor:Binds 1 4Fe-4S cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.,function:Catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. May also have a methyltransferase activity.,similarity:Belongs to the ELP3 family.,similarity:Contains 1 N-acetyltransferase domain.,subunit:Component of the RNA polymerase II elongator complex (Elongator), which consists of IKBKAP/ELP1, STIP1/ELP2, ELP3, ELP4, and two yet unidentified proteins, p30 and p38. IKBKAP/ELP1, STIP1/ELP2 and ELP3 form the Elongator core complex. Elongator associ
  • Species: Human;Mouse
  • Range: WB;ELISA
  • Protein: Elongator complex protein 3 (hELP3) (EC 2.3.1.48)
  • DA: 60kD
View full details