• ZNRF1 Polyclonal Antibody
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Upingbio

YP-Ab-05566-100UL

ZNRF1 Polyclonal Antibody

ZNRF1 Polyclonal Antibody

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  • Gene Name: ZNRF1 NIN283
  • Immunogen: Synthesized peptide derived from part region of human protein
  • Specificity: ZNRF1 Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: This gene encodes an E3 ubiquitin-protein ligase that plays a role in neural-cell differentiation. Overexpression of this gene causes neurite-like elongation. The encoded protein contains both a zinc finger and a RING finger motif and is localized in the endosome/lysosome compartment, indicating that it may be involved in ubiquitin-mediated protein modification, and in synaptic vessicle membranes in neurons. [provided by RefSeq, Feb 2012],
  • Function: domain:The RING-type zinc finger domain is required for E3 ligase activity.,function:E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to substrates. May play a role in the establisment and maintenance of neuronal transmission and plasticity via its ubiquitin-protein ligase activity.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 RING-type zinc finger.,subcellular location:Associated with synaptic vesicle membranes in neurons.,tissue specificity:Expressed primarily in the nervous system, with expression higher in developing brain relative to adult. Expressed at low levels in testis and thymus.,
  • Species: Human;Mouse
  • Range: WB;ELISA
  • Protein: E3 ubiquitin-protein ligase ZNRF1 (EC 6.3.2.-) (Nerve injury-induced gene 283 protein) (Zinc/RING finger protein 1)
  • DA: 24kD
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