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SKU:YP-Ab-05509-100UL
DOC11 Polyclonal Antibody
DOC11 Polyclonal Antibody
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- Gene Name: DOCK11 ZIZ2
- Immunogen: Synthesized peptide derived from part region of human protein
- Specificity: DOC11 Polyclonal Antibody detects endogenous levels of protein.
- Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: domain:The DHR-2 domain is necessary for the GEF activity.,function:Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP.,miscellaneous:'Zizim' means 'spike' in Hebrew.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the DOCK family.,similarity:Contains 1 DHR-1 (CZH-1) domain.,similarity:Contains 1 DHR-2 (CZH-2) domain.,similarity:Contains 1 PH domain.,subunit:Interacts with CDC42.,
- Function: domain:The DHR-2 domain is necessary for the GEF activity.,function:Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP.,miscellaneous:'Zizim' means 'spike' in Hebrew.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the DOCK family.,similarity:Contains 1 DHR-1 (CZH-1) domain.,similarity:Contains 1 DHR-2 (CZH-2) domain.,similarity:Contains 1 PH domain.,subunit:Interacts with CDC42.,
- Species: Human;Mouse
- Range: WB;ELISA
- Protein: Dedicator of cytokinesis protein 11 (Activated Cdc42-associated guanine nucleotide exchange factor) (ACG) (Zizimin-2)
- DA: 228kD
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