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Upingbio
SKU:YP-Ab-05467-100UL
CHD6 Polyclonal Antibody
CHD6 Polyclonal Antibody
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- Gene Name: CHD6 CHD5 KIAA1335 RIGB
- Immunogen: Synthesized peptide derived from part region of human protein
- Specificity: CHD6 Polyclonal Antibody detects endogenous levels of protein.
- Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: IHC-p 1:50-300. IF 1:50-200
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: This gene encodes a member of the SNF2/RAD54 helicase protein family. The encoded protein contains two chromodomains, a helicase domain, and an ATPase domain. Several multi-subunit protein complexes remodel chromatin to allow patterns of cell type-specific gene expression, and the encoded protein is thought to be a core member of one or more of these chromatin remodeling complexes. The encoded protein may function as a transcriptional repressor and is involved in the cellular repression of influenza virus replication. [provided by RefSeq, Jul 2013],
- Function: function:Probable transcription regulator.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:The sequence differs from position 1528 onward for unknown reasons.,similarity:Belongs to the SNF2/RAD54 helicase family.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,similarity:Contains 2 chromo domains.,tissue specificity:Ubiquitous.,
- Species: Human;Rat;Mouse;
- Range: IHC;IF
- Protein: Chromodomain-helicase-DNA-binding protein 6 (CHD-6) (EC 3.6.4.12) (ATP-dependent helicase CHD6) (Radiation-induced gene B protein)
- DA: 298kD
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