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Upingbio
SKU:YP-Ab-05401-100UL
CABP4 Polyclonal Antibody
CABP4 Polyclonal Antibody
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- Gene Name: CABP4
- Immunogen: Synthesized peptide derived from part region of human protein
- Specificity: CABP4 Polyclonal Antibody detects endogenous levels of protein.
- Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: This gene encodes a member of the CABP family of calcium binding protein characterized by four EF-hand motifs. Mutations in this gene are associated with congenital stationary night blindness type 2B. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],
- Function: disease:Defects in CABP4 are the cause of congenital stationary night blindness type 2B (CSNB2B) [MIM:610427]. Congenital stationary night blindness is a non-progressive retinal disorder characterized by impaired night vision.,function:May play a role in normal synaptic function, probably through regulation of Ca(2+) influx and neurotransmitter release in photoreceptor synaptic terminals. Modulator of CACNA1F, shifting the activation range to more hyperpolarized voltages.,similarity:Contains 4 EF-hand domains.,subcellular location:Found in rod spherules and cone pedicles of the presynapses from both types of photoreceptors.,subunit:Interacts with CACNA1F.,
- Species: Human;Mouse
- Range: WB;ELISA
- Protein: Calcium-binding protein 4 (CaBP4)
- DA: 30kD
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