• ABLM1 Polyclonal Antibody
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Upingbio

YP-Ab-05268-100UL

ABLM1 Polyclonal Antibody

ABLM1 Polyclonal Antibody

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  • Gene Name: ABLIM1 ABLIM KIAA0059 LIMAB1
  • Immunogen: Synthesized peptide derived from human protein . at AA range: 520-600
  • Specificity: ABLM1 Polyclonal Antibody detects endogenous levels of protein.
  • Composition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: This gene encodes a cytoskeletal LIM protein that binds to actin filaments via a domain that is homologous to erythrocyte dematin. LIM domains, found in over 60 proteins, play key roles in the regulation of developmental pathways. LIM domains also function as protein-binding interfaces, mediating specific protein-protein interactions. The protein encoded by this gene could mediate such interactions between actin filaments and cytoplasmic targets. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
  • Function: function:May act as scaffold protein (By similarity). May play a role in the development of the retina. Has been suggested to play a role in axon guidance.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 HP (headpiece) domain.,similarity:Contains 2 LIM zinc-binding domains.,similarity:Contains 4 LIM zinc-binding domains.,subcellular location:Associated with the cytoskeleton.,subunit:Binds F-actin. Interacts with ABRA.,tissue specificity:Detected in liver, heart, skeletal muscle, brain and retina, where it is concentrated in the inner segment and in the outer plexiform layers.,
  • Species: Human;Mouse
  • Range: WB;ELISA
  • Protein: Actin-binding LIM protein 1 (abLIM-1) (Actin-binding LIM protein family member 1) (Actin-binding double zinc finger protein) (LIMAB1) (Limatin)
  • DA: 85kD
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